Drugi trening na torze w Meksyku za nami. Nico Rosberg był najszybszy przed kierowcami Red Bulla. Tegoroczny mistrz świata Lewis Hamilton był dopiero czwarty. Za nim uplasowali się kierowcy Ferrari.
| Poz | Nr | Kierowca | Zespół | Czas | Strata | Okr |
| 1 | 6 | Nico Rosberg | Mercedes | 1’21.531 | | 36 |
| 2 | 26 | Daniil Kvyat | Red Bull-Renault | 1’21.776 | 0.245 | 27 |
| 3 | 3 | Daniel Ricciardo | Red Bull-Renault | 1’21.868 | 0.337 | 28 |
| 4 | 44 | Lewis Hamilton | Mercedes | 1’21.961 | 0.430 | 33 |
| 5 | 5 | Sebastian Vettel | Ferrari | 1’21.984 | 0.453 | 32 |
| 6 | 7 | Kimi Raikkonen | Ferrari | 1’22.399 | 0.868 | 33 |
| 7 | 77 | Valtteri Bottas | Williams-Mercedes | 1’22.721 | 1.190 | 28 |
| 8 | 14 | Fernando Alonso | McLaren-Honda | 1’22.993 | 1.462 | 36 |
| 9 | 22 | Jenson Button | McLaren-Honda | 1’23.109 | 1.578 | 25 |
| 10 | 19 | Felipe Massa | Williams-Mercedes | 1’23.289 | 1.758 | 32 |
| 11 | 27 | Nico Hulkenberg | Force India-Mercedes | 1’23.290 | 1.759 | 34 |
| 12 | 13 | Pastor Maldonado | Lotus-Mercedes | 1’23.363 | 1.832 | 24 |
| 13 | 55 | Carlos Sainz Jnr | Toro Rosso-Renault | 1’23.364 | 1.833 | 41 |
| 14 | 12 | Felipe Nasr | Sauber-Ferrari | 1’23.430 | 1.899 | 39 |
| 15 | 11 | Sergio Perez | Force India-Mercedes | 1’23.597 | 2.066 | 33 |
| 16 | 8 | Romain Grosjean | Lotus-Mercedes | 1’23.614 | 2.083 | 26 |
| 17 | 9 | Marcus Ericsson | Sauber-Ferrari | 1’24.533 | 3.002 | 34 |
| 18 | 53 | Alexander Rossi | Manor-Ferrari | 1’25.940 | 4.409 | 29 |
| 19 | 28 | Will Stevens | Manor-Ferrari | 1’26.968 | 5.437 | 28 |
| 20 | 33 | Max Verstappen | Toro Rosso-Renault | | | 2 |
